Our research team will be part of SynBioCZ – Elevating Czech Excellence in Synthetic Biology for Climate Resilience, a newly funded Horizon Europe Twinning project.

BKralova Lab
Welcome to the B. Kralova Lab!
We are established at Masaryk University, Faculty of Pharmacy, Department of Molecular Pharmacy, and we are proud to be part of the Czech Antarctic Research Programme – Polar-Bio-Lab.
We are a team dedicated to exploring the fascinating world of Antarctic extremophilic microorganisms. Our work focuses on uncovering the biosynthetic potential of these unique bacteria, with a particular emphasis on the discovery of novel antimicrobial compounds that could contribute to the global fight against antimicrobial resistance.
Beyond antimicrobial discovery, we are deeply interested in the diversity and adaptive strategies of Antarctic microbiota — how life thrives under extreme conditions of cold, dryness, and isolation. By studying these remarkable adaptations, we aim to identify new molecules and mechanisms with potential biomedical and biotechnological applications.
At the core of our research lies a shared curiosity for the unseen microbial world and its potential to inspire innovative solutions to pressing health and environmental challenges.
News
New paper: Meet the kineochelins!
Our new study, "Kineochelins—A New Group of Siderophores From an Antarctic Bacterium," has been published in Microbial Biotechnology.
World Antimicrobial Awareness Week 2025
Antimicrobial resistance (AMR) remains one of the most urgent global health challenges of our time. Every year, more pathogens become resistant to available antibiotics, threatening the effectiveness of routine medical care and increasing the burden on healthcare systems worldwide. As researchers, clinicians, and citizens, we all play a role in...
Our GACR funded project is in the news!
Our research on RiPPs (ribosomally-synthesized and post-translationally modified peptides) from Antarctic soil microbiomes, supported by the Czech Science Foundation (GAČR), project ID: 25-17343S, was recently featured in Czech national media. In an interview for iRozhlas, we discussed our research together with my PhD student Peter—who recently...
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