Welcome to the B. Kralova Lab!
We are a team dedicated to exploring the fascinating world of Antarctic extremophilic microorganisms. Our work focuses on uncovering the biosynthetic potential of these unique bacteria, with a particular emphasis on the discovery of novel antimicrobial compounds that could contribute to the global fight against antimicrobial resistance (AMR).
Beyond antimicrobial discovery, we are deeply interested in the diversity and adaptive strategies of Antarctic microbiota — how life thrives under extreme conditions of cold, dryness, and isolation. By studying these remarkable adaptations, we aim to identify new molecules and mechanisms with potential biomedical and biotechnological applications.
At the core of our research lies a shared curiosity for the unseen microbial world and its potential to inspire innovative solutions to pressing health and environmental challenges.
Antimicrobial resistance (AMR) remains one of the most urgent global health challenges of our time. Every year, more pathogens become resistant to available antibiotics, threatening the effectiveness of routine medical care and increasing the burden on healthcare systems worldwide. As researchers, clinicians, and citizens, we all play a role in...
Our research on RiPPs (ribosomally-synthesized and post-translationally modified peptides) from Antarctic soil microbiomes, supported by the Czech Science Foundation (GAČR), project ID: 25-17343S, was recently featured in Czech national media. In an interview for iRozhlas, we discussed our research together with my PhD student Peter—who recently...
One of the most inspiring milestones of this summer was the opportunity to take part in the Dutch Royal State Visit and the Czech–Dutch Business Forum, where I was honored to be selected as a Creative Hero 2023. This recognition allowed me to share my scientific journey—returning to the Czech Republic after years abroad—and to present the...
I am honoured to share that I have been awarded the MASH StG/CoG grant from the Grant Agency of Masaryk University (GAMU), following a rigorous two-round selection process. This highly competitive four-year funding will support me in establishing a new research group at the Faculty of Pharmacy, Department of Molecular Pharmacy. Out of nine...
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